Mesenchymal sel sel wani yanki ne na sel masu ƙarfi masu ƙarfi waɗanda za a iya keɓance su daga mesoderm.Tare da sabuntawar sake maimaita kansu da halayen bambance-bambancen shugabanci da yawa, suna da babban damar yin amfani da magunguna daban-daban.Mesenchymal stem Kwayoyin suna da na musamman na rigakafi phenotype da ikon sarrafa rigakafi.Don haka, an riga an yi amfani da sel mai tushe na mesenchymal sosai wajen dashen sel, injiniyan nama da dashen gabobin jiki.Kuma Bayan waɗannan aikace-aikacen, ana amfani da su azaman kayan aiki mai kyau a cikin injiniyan nama azaman ƙwayoyin iri a cikin jerin gwaje-gwajen bincike na asali da na asibiti.
Countstar Rigel na iya sa ido kan maida hankali, iyawa, bincike na apoptosis da halayen phenotype (da canje-canjen su) yayin samarwa da bambance-bambancen waɗannan ƙwayoyin kara.Countstar Rigel kuma yana da fa'ida wajen samun ƙarin bayanan ilimin halittar jiki, wanda filin haske na dindindin ya bayar da rikodin hoto na tushen haske yayin duk aikin sa ido kan ingancin tantanin halitta.Countstar Rigel yana ba da hanya mai sauri, ƙwaƙƙwara kuma abin dogaro don ingantaccen sarrafa ƙwayoyin kara.
Kulawa da Kwarewa na MSCs a cikin Magungunan Farfaɗo
Hoto 1 Kula da iyawa da ƙidayar sel na mesenchymal stem cell (MSCs) don amfani a cikin hanyoyin maganin tantanin halitta
Kwayoyin Stem yana ɗaya daga cikin mafi kyawun jiyya a cikin farfadowar ƙwayoyin cuta.Daga girbi na MSC zuwa jiyya, yana da mahimmanci don dorewar ingantaccen ƙwayar ƙwayar ƙwayar cuta yayin duk matakan samar da kwayar halitta (Hoto na 1).Countstar's stem cell counter yana sa ido kan iyawar tantanin halitta da maida hankali don taka muhimmiyar rawa wajen sarrafa inganci.
Kula da Canje-canjen Halittu na MSC bayan Jirgin
Countstar Rigel kuma ya ƙaddara diamita da tarawa.An canza diamita na AdMSCs sosai bayan sufuri idan aka kwatanta da kafin jigilar kaya.Diamita na kafin jigilar kaya shine 19µm, amma ya karu zuwa 21µm bayan sufuri.Jimlar kafin jigilar kaya shine 20%, amma ya karu zuwa 25% bayan sufuri.Daga hotunan da Countstar Rigel ya ɗauka, an canza nau'in AdMSCs sosai bayan sufuri.An nuna sakamakon a hoto na 3.
Gano AdMSCs a cikin Halin Halitta
A halin yanzu shine mafi ƙarancin matakan gwaji na tantancewar tantancewar MSCs an jera su a cikin bayanin ƙungiyar ƙasa ta duniya don riga a 2006.
Ganewar Apoptosis da sauri a cikin MSCs tare da FITC Conjugated Annexin-V da 7-ADD Gabatarwa
Za a iya gano Apoptosis ta salula tare da haɗin FITC annexin-V da 7-ADD.PS yawanci ana samunsa ne kawai akan leaflet ɗin cikin cell na membran plasma a cikin sel lafiya, amma a farkon apoptosis, membrane asymmetry yana ɓacewa kuma PS yana jujjuya zuwa takardan waje.
Hoto 6 Gano Apoptosis a cikin MSCs ta Countstar Rigel
A. Duban gani na hoton haske na Gane Apoptosis a cikin MSCs
B. Yada makircin Apoptosis a cikin MSCs ta FCS bayyana
C. Kashi na yawan adadin tantanin halitta bisa % al'ada, % apoptotic, da % necrotic/masu matuƙar ƙarshen-kwayoyin apoptotic.
